SERPINC1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against native SERPINC1.
Immunogen
Native purified SERPINC1 from human plasma.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS, pH 7.5 (0.02% sodium azide, 50% glycerol (v/v))
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Enzyme Immunoassay
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Gene Info — SERPINC1
Entrez GeneID
462Gene Name
SERPINC1
Gene Alias
AT3, ATIII, MGC22579
Gene Description
serpin peptidase inhibitor, clade C (antithrombin), member 1
Omim ID
107300Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency. [provided by RefSeq
Other Designations
OTTHUMP00000035393|antithrombin (aa 375-432)|antithrombin III|coding sequence signal peptide antithrombin part 1|serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1|signal peptide antithrombin part 1
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Interactome
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Disease
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