IGF1R (phospho Y1280) polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of extract from 293 cells untreated or treated with insulin using IGF1R (phospho Y1280) polyclonal antibody (Cat # PAB18914).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic phosphopeptide of IGF1R.
Immunogen
Synthetic phosphopeptide corresponding to amino acids (S-F-Y(p)-Y-S) residues surrounding Y1280 of human IGF1R.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of extract from 293 cells untreated or treated with insulin using IGF1R (phospho Y1280) polyclonal antibody (Cat # PAB18914). -
Gene Info — IGF1R
Entrez GeneID
3480Gene Name
IGF1R
Gene Alias
CD221, IGFIR, JTK13, MGC142170, MGC142172, MGC18216
Gene Description
insulin-like growth factor 1 receptor
Omim ID
147370Gene Ontology
HyperlinkGene Summary
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq
Other Designations
soluble IGF1R variant 1|soluble IGF1R variant 2
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Interactome
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Pathway
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Disease
- Abortion
- Adenocarcinoma
- Adenoma
- Alzheimer disease
- Anemia
- Aneuploidy
- Atherosclerosis
- Bacteremia
- Barrett Esophagus
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