MTHFR polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of MTHFR.
Immunogen
A synthetic peptide corresponding to human MTHFR.
Sequence
C-NRPTQNARETEAP
Host
Goat
Theoretical MW (kDa)
74.5
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:16000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — MTHFR
Entrez GeneID
4524Protein Accession#
NP_005948.3Gene Name
MTHFR
Gene Alias
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Gene Description
5,10-methylenetetrahydrofolate reductase (NADPH)
Gene Ontology
HyperlinkGene Summary
Methylenetetrahydrofolate reductase (EC 1.5.1.20) catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a cosubstrate for homocysteine remethylation to methionine.[supplied by OMIM
Other Designations
OTTHUMP00000002367|OTTHUMP00000002368|methylenetetrahydrofolate reductase intermediate form
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Interactome
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Pathway
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Disease
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Publication Reference
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Functional polymorphisms in folate metabolism genes influence the risk of meningioma and glioma.
Bethke L, Webb E, Murray A, Schoemaker M, Feychting M, Lonn S, Ahlbom A, Malmer B, Henriksson R, Auvinen A, Kiuru A, Salminen T, Johansen C, Christensen HC, Muir K, McKinney P, Hepworth S, Dimitropoulou P, Lophatananon A, Swerdlow A, Houlston R.
Cancer Epidemiology, Biomarkers & Prevention : A Publication of the American Association for Canc 2008 May; 17(5):1195.
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Functional polymorphisms in folate metabolism genes influence the risk of meningioma and glioma.
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