CDH2 polyclonal antibody
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More Files
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Western Blot (Tissue lysate)
Western blot analysis of tissue extracts with CDH2 polyclonal antibody (Cat # PAB17213).
Lane 1 : rat liver.
Lane 2 : rat liver.
Lane 3 : rat brain.
Lane 4 : rat testicular tissue.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CDH2.
Immunogen
A synthetic peptide corresponding to amino acids at internal region of human CDH2.
Host
Rabbit
Theoretical MW (kDa)
99
Reactivity
Human, Rat
Specificity
The synthetic peptide of this antibody is identical to the rat sequence.
Form
Lyophilized
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from 0.9 mg NaCl, 0.2 mg Na2HPO4 (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)
Storage Instruction
Store at -20°C on dry atmosphere.
After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide and thimerosal: POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of tissue extracts with CDH2 polyclonal antibody (Cat # PAB17213).
Lane 1 : rat liver.
Lane 2 : rat liver.
Lane 3 : rat brain.
Lane 4 : rat testicular tissue. -
Gene Info — CDH2
Entrez GeneID
1000Gene Name
CDH2
Gene Alias
CD325, CDHN, CDw325, NCAD
Gene Description
cadherin 2, type 1, N-cadherin (neuronal)
Omim ID
114020Gene Ontology
HyperlinkGene Summary
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product. [provided by RefSeq
Other Designations
N-cadherin 1|cadherin 2, N-cadherin (neuronal)|cadherin 2, type 1|calcium-dependent adhesion protein, neuronal|neural cadherin
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Interactome
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Pathway
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Disease
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Publication Reference
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Genomic structure and chromosomal mapping of the mouse N-cadherin gene.
Miyatani S, Copeland NG, Gilbert DJ, Jenkins NA, Takeichi M.
PNAS 1992 Sep; 89(18):8443.
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N-cadherin gene maps to human chromosome 18 and is not linked to the E-cadherin gene.
Walsh FS, Barton CH, Putt W, Moore SE, Kelsell D, Spurr N, Goodfellow PN.
Journal of Neurochemistry 1990 Sep; 55(3):805.
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Genomic structure and chromosomal mapping of the mouse N-cadherin gene.
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