TNFRSF10B polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Cell lysate)
Jurkat cell lystates were analyzed by Western blotting. Using TNFRSF10B polyclonal antibody (Cat # PAB14350).
Flow Cytometry
Jurkat cells were incubated with the isotype control and TNFRSF10B polyclonal antibody (Cat # PAB14350) and then stained with Goat Anti-Rabbit IgG (H+L), human/mouse ads-FITC.
-
Specification
Product Description
Rabbit polyclonal antibody raised against recombinant TNFRSF10B.
Immunogen
Recombinant protein corresponding to human TNFRSF10B.
Host
Rabbit
Reactivity
Human
Specificity
human DR5.
Form
Liquid
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In 100 mM BBS, pH 8.2
Storage Instruction
Store at 4°C.
-
Applications
Western Blot (Cell lysate)
Jurkat cell lystates were analyzed by Western blotting. Using TNFRSF10B polyclonal antibody (Cat # PAB14350).Flow Cytometry
Jurkat cells were incubated with the isotype control and TNFRSF10B polyclonal antibody (Cat # PAB14350) and then stained with Goat Anti-Rabbit IgG (H+L), human/mouse ads-FITC. -
Gene Info — TNFRSF10B
Entrez GeneID
8795Gene Name
TNFRSF10B
Gene Alias
CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9
Gene Description
tumor necrosis factor receptor superfamily, member 10b
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq
Other Designations
Fas-like protein|OTTHUMP00000123492|TNF-related apoptosis-inducing ligand receptor 2|TRAIL receptor 2|apoptosis inducing protein TRICK2A/2B|apoptosis inducing receptor TRAIL-R2|cytotoxic TRAIL receptor-2|death domain containing receptor for TRAIL/Apo-2L|d
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
2-methoxyestradiol up-regulates death receptor 5 and induces apoptosis through activation of the extrinsic pathway.
LaVallee TM, Zhan XH, Johnson MS, Herbstritt CJ, Swartz G, Williams MS, Hembrough WA, Green SJ, Pribluda VS.
Cancer Research 2003 Jan; 63(2):468.
-
Pretreatment with paclitaxel enhances apo-2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of prostate cancer cells by inducing death receptors 4 and 5 protein levels.
Nimmanapalli R, Perkins CL, Orlando M, O'Bryan E, Nguyen D, Bhalla KN.
Cancer Research 2001 Jan; 6(12):759.
Application：WB-Ce, Human, PC-3, DU145, LNCaP cells.
-
An antagonist decoy receptor and a death domain-containing receptor for TRAIL.
Pan G, Ni J, Wei YF, Yu G, Gentz R, Dixit VM.
Science 1997 Aug; 277(5327):815.
-
2-methoxyestradiol up-regulates death receptor 5 and induces apoptosis through activation of the extrinsic pathway.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com