SEMA3B polyclonal antibody
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More Files
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Western Blot (Tissue lysate)
Western blot analysis of SEMA3B in mouse E16 cerebellum lysate with SEMA3B polyclonal antibody (Cat # PAB12040).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SEMA3B.
Immunogen
A synthetic peptide corresponding to amino acids 100-200 of human SEMA3B.
Host
Rabbit
Reactivity
Bovine, Dog, Human, Mouse, Rat
Specificity
This antibody is specific to SEMA 3B.
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western Blot (1:5000-1:20000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris-glycine, 150 mM NaCl (0.05% sodium azide)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of SEMA3B in mouse E16 cerebellum lysate with SEMA3B polyclonal antibody (Cat # PAB12040). -
Gene Info — SEMA3B
Entrez GeneID
7869Gene Name
SEMA3B
Gene Alias
FLJ34863, LUCA-1, SEMA5, SEMAA, SemA, semaV
Gene Description
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
Omim ID
601281Gene Ontology
HyperlinkGene Summary
The semaphorin/collapsin family of molecules plays a critical role in the guidance of growth cones during neuronal development. The secreted protein encoded by this gene family member is important in axonal guidance and has been shown to act as a tumor suppressor by inducing apoptosis. [provided by RefSeq
Other Designations
semaphorin 3B|semaphorin A|semaphorin V
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Interactome
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Pathway
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Disease
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Publication Reference
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Semaphorin 3B (SEMA3B) induces apoptosis in lung and breast cancer, whereas VEGF165 antagonizes this effect.
Castro-Rivera E, Ran S, Thorpe P, Minna JD.
PNAS 2004 Aug; 101(31):11432.
Application：WB-Tr, Monkey, COS-7 cells.
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Inhibition of lung cancer cell growth and induction of apoptosis after reexpression of 3p21.3 candidate tumor suppressor gene SEMA3B.
Tomizawa Y, Sekido Y, Kondo M, Gao B, Yokota J, Roche J, Drabkin H, Lerman MI, Gazdar AF, Minna JD.
PNAS 2001 Nov; 98(24):13954.
Application：WB-Tr, Human, H1299 cells.
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Semaphorin 3B (SEMA3B) induces apoptosis in lung and breast cancer, whereas VEGF165 antagonizes this effect.
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