SERPINA3 (Human) Native Protein
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Specification
Product Description
Human SERPINA3 native protein from normal human plasma.
Sequence
MERMLPLLALGLLAAGFCPAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPETLKRWRDSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQA
Host
Human
Theoretical MW (kDa)
64
Form
Lyophilized
Preparation Method
Native protein purified from normal human plasma.
Purity
> 90% by SDS-PAGE
Storage Buffer
Lyophilized from 20 mM Tris-HCl, 150 mM NaCl, pH 7.4.
Storage Instruction
Store at -80°C on dry atmosphere.
Reconstitute 0.1 mg of the protein with 0.1 mL of reagent grade water to generate a 1 mg/mL solution. Allow the protein solution to sit for 10 minutes with gentle agitaton prior to use. After reconstitution with reagent grade water, store at -60°C or lower.
Aliquot to avoid repeated freezing and thawing. -
Applications
SDS-PAGE
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Gene Info — SERPINA3
Entrez GeneID
12Protein Accession#
P01011Gene Name
SERPINA3
Gene Alias
AACT, ACT, GIG24, GIG25, MGC88254
Gene Description
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
Omim ID
107280Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. [provided by RefSeq
Other Designations
alpha-1-antichymotrypsin|antichymotrypsin|growth-inhibiting protein 24|growth-inhibiting protein 25|serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3|serine (or cysteine) proteinase inhibitor, clade A, memb
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Interactome
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Disease
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