DNMT1 monoclonal antibody, clone 4G11-C7
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More Files
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Western Blot (Cell lysate)
Western blot analysis of Jurkat lysates with DNMT1 monoclonal antibody, clone 4G11-C7 (Cat # MAB11764) at 1:100 dilution.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant DNMT1.
Immunogen
Recombinant protein corresponding to amino acids of 620-950 of human DNMT1.
Host
Mouse
Reactivity
Human, Mouse, Zebra fish
Specificity
The antibody will cross-react with mouse DNMT1.
Form
Liquid
Purification
Protein G Purification
Isotype
IgG1 Kappa
Recommend Usage
Immunohistochemistry (1:1000)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (50% glycerol, 0.09% sodium azide).
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
ChIP
Western Blot (Cell lysate)
Western blot analysis of Jurkat lysates with DNMT1 monoclonal antibody, clone 4G11-C7 (Cat # MAB11764) at 1:100 dilution.Immunohistochemistry
Immunoprecipitation
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Gene Info — DNMT1
Entrez GeneID
1786Protein Accession#
NP_001370Gene Name
DNMT1
Gene Alias
AIM, CXXC9, DNMT, FLJ16293, MCMT, MGC104992
Gene Description
DNA (cytosine-5-)-methyltransferase 1
Omim ID
126375Gene Ontology
HyperlinkGene Summary
DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
CXXC finger protein 9|DNA methyltransferase 1
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Interactome
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Pathway
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Disease
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Publication Reference
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Sesamol Epigenetically Induces Estrogen Receptor α Re-expression by Upregulating miR-370-3p in Estrogen Receptor α-Negative Breast Cancer.
Xiao Ma, Juhong Wang, Guifen Hu, Yinggang Chen, Xiaoling Hu, Yijia Zhu, Linchao Ding, Shilong Ning.
Journal of Agricultural and Food Chemistry 2021 Aug; 69(31):8737.
Application：ChIP, IHC-P, WB-Ce, WB-Tr, Human, Mouse, Hs-578T, MDA-MB-231 cells, Mouse tumors.
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Sesamol Epigenetically Induces Estrogen Receptor α Re-expression by Upregulating miR-370-3p in Estrogen Receptor α-Negative Breast Cancer.
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