IGF1R monoclonal antibody, clone 3C8B1
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More Files
- More Functions
Western Blot (Recombinant protein)
Western blot analysis using IGF1R monoclonal antibody, clone 3C8B1 (Cat # MAB10692) against truncated IGF1R recombinant protein.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human gastric adenocarcinoma (A) , colon adenocarcinoma (B) , endometrial carcinoma (uterus) (C) , ovary adenocarcinoma (D) , lung squamous cell carcinoma (E) , stomach epithelium mucosae (F) , showing membrane localization using IGF1R monoclonal antibody, clone 3C8B1 (Cat # MAB10692) with DAB staining.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant IGF1R.
Immunogen
Recombinant protein corresponding to human IGF1R.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG2b
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:200-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Recombinant protein)
Western blot analysis using IGF1R monoclonal antibody, clone 3C8B1 (Cat # MAB10692) against truncated IGF1R recombinant protein.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human gastric adenocarcinoma (A) , colon adenocarcinoma (B) , endometrial carcinoma (uterus) (C) , ovary adenocarcinoma (D) , lung squamous cell carcinoma (E) , stomach epithelium mucosae (F) , showing membrane localization using IGF1R monoclonal antibody, clone 3C8B1 (Cat # MAB10692) with DAB staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — IGF1R
Entrez GeneID
3480Gene Name
IGF1R
Gene Alias
CD221, IGFIR, JTK13, MGC142170, MGC142172, MGC18216
Gene Description
insulin-like growth factor 1 receptor
Omim ID
147370Gene Ontology
HyperlinkGene Summary
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq
Other Designations
soluble IGF1R variant 1|soluble IGF1R variant 2
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Interactome
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Pathway
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Disease
- Abortion
- Adenocarcinoma
- Adenoma
- Alzheimer disease
- Anemia
- Aneuploidy
- Atherosclerosis
- Bacteremia
- Barrett Esophagus
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