APOE monoclonal antibody, clone 1H4
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More Files
- More Functions
Western Blot (Transfected lysate)
Western blot analysis using APOE monoclonal antibody, clone 1H4 (Cat # MAB10490) against HEK293 (1) and ApoE (aa : 20-267)-hIgGFc transfected HEK293 (2) cell lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human liver cancer tissues (A) and brain tissues (B) using APOE monoclonal antibody, clone 1H4 (Cat # MAB10490) with DAB staining.
Enzyme-linked Immunoabsorbent Assay
ELISA detection with APOE monoclonal antibody, clone 1H4 (Cat # MAB10490).
Flow Cytometry
Flow cytometric analysis of HepG2 cells using APOE monoclonal antibody, clone 1H4 (Cat # MAB10490) (green) and negative control (purple).
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant APOE.
Immunogen
Recombinant protein corresponding to human APOE.
Host
Mouse
Theoretical MW (kDa)
36
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:200-1:1000)
Flow cytometry (1:200-1:400)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis using APOE monoclonal antibody, clone 1H4 (Cat # MAB10490) against HEK293 (1) and ApoE (aa : 20-267)-hIgGFc transfected HEK293 (2) cell lysate.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human liver cancer tissues (A) and brain tissues (B) using APOE monoclonal antibody, clone 1H4 (Cat # MAB10490) with DAB staining.Enzyme-linked Immunoabsorbent Assay
ELISA detection with APOE monoclonal antibody, clone 1H4 (Cat # MAB10490).Flow Cytometry
Flow cytometric analysis of HepG2 cells using APOE monoclonal antibody, clone 1H4 (Cat # MAB10490) (green) and negative control (purple). -
Gene Info — APOE
Entrez GeneID
348Gene Name
APOE
Gene Alias
AD2, LPG, MGC1571, apoprotein
Gene Description
apolipoprotein E
Gene Ontology
HyperlinkGene Summary
Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq
Other Designations
apolipoprotein E3
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Interactome
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Disease
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