SERPINC1 (Human) ELISA Kit
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Specification
Product Description
SERPINC1 (Human) ELISA Kit is a competitive enzyme immunoassay for the quantitative measurement of human SERPINC1.
Suitable Sample
Plasma, Serum
Sample Volume
25 uL
Label
Peroxidase-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
0.063 to 4 ug/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Storage Instruction
Store components of the kit at 4°C or -20°C as described in the protocol.
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Applications
Quantification
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Gene Info — SERPINC1
Entrez GeneID
462Gene Name
SERPINC1
Gene Alias
AT3, ATIII, MGC22579
Gene Description
serpin peptidase inhibitor, clade C (antithrombin), member 1
Omim ID
107300Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency. [provided by RefSeq
Other Designations
OTTHUMP00000035393|antithrombin (aa 375-432)|antithrombin III|coding sequence signal peptide antithrombin part 1|serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1|signal peptide antithrombin part 1
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Interactome
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Pathway
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Disease
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Publication Reference
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Quantitative proteomic analysis exploring progression of colorectal cancer: Modulation of the serpin family.
Peltier J, Roperch JP, Audebert S, Borg JP, Camoin L.
Journal of Proteomics 2016 Oct; 148:139.
Application:ELISA, Human, Serum.
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Quantitative proteomic analysis exploring progression of colorectal cancer: Modulation of the serpin family.
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