PTPN22 monoclonal antibody (M02), clone 1A6
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More Files
- More Functions
Immunofluorescence
Immunofluorescence of monoclonal antibody to PTPN22 on HeLa cell . [antibody concentration 10 ug/ml]
Western Blot detection against Immunogen (37.18 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PTPN22.
Immunogen
PTPN22 (NP_057051.2, 10 a.a. ~ 113 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
FLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRYKDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDF
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (60); Rat (63)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.18 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to PTPN22 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — PTPN22
Entrez GeneID
26191GeneBank Accession#
NM_015967Protein Accession#
NP_057051.2Gene Name
PTPN22
Gene Alias
LYP, Lyp1, Lyp2, PEP, PTPN8
Gene Description
protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
Gene Ontology
HyperlinkGene Summary
This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq
Other Designations
OTTHUMP00000013720|lymphoid-specific protein tyrosine phosphatase|protein tyrosine phosphatase, non-receptor type 8
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Interactome
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Disease
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