MAP3K7IP2 (Human) IP-WB Antibody Pair
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More Files
- More Functions
Immunoprecipitation of MAP3K7IP2 transfected lysate using rabbit polyclonal anti-MAP3K7IP2 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-MAP3K7IP2.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of MAP3K7IP2 transfected lysate using rabbit polyclonal anti-MAP3K7IP2 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-MAP3K7IP2.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-MAP3K7IP2 (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-MAP3K7IP2 (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — MAP3K7IP2
Entrez GeneID
23118Gene Name
MAP3K7IP2
Gene Alias
FLJ21885, KIAA0733, TAB2
Gene Description
mitogen-activated protein kinase kinase kinase 7 interacting protein 2
Omim ID
605101Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. [provided by RefSeq
Other Designations
OTTHUMP00000017388|OTTHUMP00000040125|TAK1-binding protein 2
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Interactome
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Pathway
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Disease
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