MAP3K7IP2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human MAP3K7IP2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human MAP3K7IP2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human MAP3K7IP2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — MAP3K7IP2
Entrez GeneID
23118GeneBank Accession#
MAP3K7IP2Gene Name
MAP3K7IP2
Gene Alias
FLJ21885, KIAA0733, TAB2
Gene Description
mitogen-activated protein kinase kinase kinase 7 interacting protein 2
Omim ID
605101Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. [provided by RefSeq
Other Designations
OTTHUMP00000017388|OTTHUMP00000040125|TAK1-binding protein 2
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