ABCG2 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Flow Cytometry
FACS analysis of negative control 293 cells (Black) and ABCG2 expressing 293 cells (Green) using ABCG2 purified MaxPab mouse polyclonal antibody.
Western Blot (Tissue lysate)
ABCG2 MaxPab polyclonal antibody. Western Blot analysis of ABCG2 expression in human liver.
Western Blot (Transfected lysate)
Western Blot analysis of ABCG2 expression in transfected 293T cell line (H00009429-T01) by ABCG2 MaxPab polyclonal antibody.
Lane 1: ABCG2 transfected lysate(72.05 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human ABCG2 protein.
Immunogen
ABCG2 (AAH21281.1, 1 a.a. ~ 655 a.a) full-length human protein.
Sequence
MSSSNVEVFIPVSQGNTNGFPATASNDLKAFTEGAVLSFHNICYRVKLKSGFLPCRKPVEKEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIINGDSTAVALNREEDFKATEIIEPSKQDKPLIEKLAEIYVNSSFYKETKAELHQLSGGEKKKKITVFKEISYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDSTGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLPMRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGNNPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKYS
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Flow Cytometry
FACS analysis of negative control 293 cells (Black) and ABCG2 expressing 293 cells (Green) using ABCG2 purified MaxPab mouse polyclonal antibody.Western Blot (Tissue lysate)
ABCG2 MaxPab polyclonal antibody. Western Blot analysis of ABCG2 expression in human liver.Western Blot (Transfected lysate)
Western Blot analysis of ABCG2 expression in transfected 293T cell line (H00009429-T01) by ABCG2 MaxPab polyclonal antibody.
Lane 1: ABCG2 transfected lysate(72.05 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — ABCG2
Entrez GeneID
9429GeneBank Accession#
NM_004827.2Protein Accession#
AAH21281.1Gene Name
ABCG2
Gene Alias
ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, MGC102821, MRX, MXR, MXR1
Gene Description
ATP-binding cassette, sub-family G (WHITE), member 2
Omim ID
603756Gene Ontology
HyperlinkGene Summary
The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. [provided by RefSeq
Other Designations
ABC transporter|ATP-binding cassette transporter G2|ATP-binding cassette, sub-family G, member 2|breast cancer resistance protein|mitoxantrone resistance protein|placenta specific MDR protein
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Interactome
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Pathway
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Disease
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