ARTN 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
ARTN transfected lysate.
Western Blot
Lane 1: ARTN transfected lysate ( 25.19 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-ARTN full-length
Host
Human
Theoretical MW (kDa)
25.19
Interspecies Antigen Sequence
Mouse (73); Rat (75)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-ARTN antibody (H00009048-B01) by Western Blots.
SDS-PAGE Gel
ARTN transfected lysate.
Western Blot
Lane 1: ARTN transfected lysate ( 25.19 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — ARTN
Entrez GeneID
9048GeneBank Accession#
BC062375Protein Accession#
AAH62375Gene Name
ARTN
Gene Alias
ENOVIN, EVN, NBN
Gene Description
artemin
Omim ID
603886Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the glial cell line-derived neurotophic factor (GDNF) family of ligands which are a group of ligands within the TGF-beta superfamily of signaling molecules. GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenerative disease. Artemin has been shown in culture to support the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. Its role in the PNS and CNS is further substantiated by its expression pattern in the proximity of these neurons. This protein is a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000009173|OTTHUMP00000009174|neublastin|neurotrophic factor|neurotrophic factor artemin
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Disease
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