TNFRSF10B 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-TNFRSF10B full-length
Host
Human
Theoretical MW (kDa)
47.9
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-TNFRSF10B antibody (H00008795-B01) by Western Blots.
SDS-PAGE Gel
TNFRSF10B transfected lysate
Western Blot
Lane 1: TNFRSF10B transfected lysate ( 47.9 KDa).
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — TNFRSF10B
Entrez GeneID
8795GeneBank Accession#
NM_003842Protein Accession#
NP_003833Gene Name
TNFRSF10B
Gene Alias
CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9
Gene Description
tumor necrosis factor receptor superfamily, member 10b
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq
Other Designations
Fas-like protein|OTTHUMP00000123492|TNF-related apoptosis-inducing ligand receptor 2|TRAIL receptor 2|apoptosis inducing protein TRICK2A/2B|apoptosis inducing receptor TRAIL-R2|cytotoxic TRAIL receptor-2|death domain containing receptor for TRAIL/Apo-2L|d
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Interactome
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Pathway
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Disease
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