FZD3 monoclonal antibody (M02), clone 1B8
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant FZD3.
Immunogen
FZD3 (NP_059108, 55 a.a. ~ 157 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
QQTAALAMEPFHPMVNLDCSRDFRPFLCALYAPICMEYGRVTLPCRRLCQRAYSECSKLMEMFGVPWPEDMECSRFPDCDEPYPRLVDLNLAGEPTEGAPVAV
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.07 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged FZD3 is approximately 1ng/ml as a capture antibody.ELISA
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Gene Info — FZD3
Entrez GeneID
7976GeneBank Accession#
NM_017412Protein Accession#
NP_059108Gene Name
FZD3
Gene Alias
Fz-3, hFz3
Gene Description
frizzled homolog 3 (Drosophila)
Omim ID
606143Gene Ontology
HyperlinkGene Summary
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development. [provided by RefSeq
Other Designations
frizzled 3
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Interactome
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Pathway
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Disease
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Publication Reference
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Identification of WNT/{beta}-CATENIN signaling pathway components in human cumulus cells.
Wang HX, Tekpetey FR, Kidder GM.
Molecular Human Reproduction 2009 Jan; 15(1):11.
Application:WB, Human, Cumulus cell.
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Identification of WNT/{beta}-CATENIN signaling pathway components in human cumulus cells.
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