TACR1 polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant TACR1.
Immunogen
TACR1 (NP_001049, 140 a.a. ~ 243 a.a) partial recombinant protein with GST tag.
Sequence
PRLSATATKVVICVIWVLALLLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQVSAK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (96); Rat (96)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.55 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — TACR1
Entrez GeneID
6869GeneBank Accession#
NM_001058Protein Accession#
NP_001049Gene Name
TACR1
Gene Alias
NK1R, NKIR, SPR, TAC1R
Gene Description
tachykinin receptor 1
Omim ID
162323Gene Ontology
HyperlinkGene Summary
This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P. [provided by RefSeq
Other Designations
NK-1 receptor|neurokinin 1 receptor|tachykinin 1 receptor (substance P receptor, neurokinin 1 receptor)|tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor)
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Interactome
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Pathway
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Disease
- Alcoholism
- Anorexia Nervosa
- Asthma
- Bipolar Disorder
- Bulimia
- Chronic Disease
- Constipation
- Cough
- Endometriosis
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Publication Reference
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Substance P (SP) enhances CCL5-induced chemotaxis and intracellular signaling in human monocytes, which express the truncated neurokinin-1 receptor (NK1R).
Chernova I, Lai JP, Li H, Schwartz L, Tuluc F, Korchak HM, Douglas SD, Kilpatrick LE.
Journal of Leukocyte Biology 2008 Oct; 85(1):154.
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Substance P (SP) enhances CCL5-induced chemotaxis and intracellular signaling in human monocytes, which express the truncated neurokinin-1 receptor (NK1R).
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