SPINK1 (Human) Matched Antibody Pair
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Specification
Product Description
This antibody pair set comes with matched antibody pair to detect and quantify protein level of human SPINK1.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (68)
Quality Control Testing
Standard curve using recombinant protein ( H00006690-P01 ) as an analyte.
Sandwich ELISA detection sensitivity ranging from 1 ng/ml to 100 ng/ml.
Supplied Product
Antibody pair set content:
1. Capture antibody: mouse monoclonal anti-SPINK1, IgG2a Kappa (100 ug)
2. Detection antibody: biotinylated mouse monoclonal anti-SPINK1, IgG2b Kappa (50 ug)
*Reagents are sufficient for at least 3-5 x 96 well plates using recommended protocols.Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
ELISA Pair (Recombinant protein)
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Gene Info — SPINK1
Entrez GeneID
6690Gene Name
SPINK1
Gene Alias
PCTT, PSTI, Spink3, TATI
Gene Description
serine peptidase inhibitor, Kazal type 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis. [provided by RefSeq
Other Designations
pancreatic secretory trypsin inhibitor|serine protease inhibitor, Kazal type 1|tumor-associated trypsin inhibitor
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Interactome
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Disease
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Publication Reference
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Pancreatic secretory trypsin inhibitor causes autocrine-mediated migration & invasion in bladder cancer & phosphorylates the EGF receptor, Akt 2 & 3, ERK1 & 2.
Marchbank T, Mahmood A, Playford RJ.
American Journal of Physiology. Renal Physiology 2013 Aug; 305(3):F382.
Application:EPair-Re, Human, 253J cells.
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Pancreatic secretory trypsin inhibitor causes autocrine-mediated migration & invasion in bladder cancer & phosphorylates the EGF receptor, Akt 2 & 3, ERK1 & 2.
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