RNASEL (Human) Recombinant Protein (Q01)
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More Files
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Specifications
Product Description
Human RNASEL partial ORF ( NP_066956, 619 a.a. - 728 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
QPGPSEHSKSFDKWTTKINECVMKKMNKFYEKRGNFYQNTVGDLLKFIRNLGEHIDEEKHKKMKLKIGDPSLYFQKTFPDLVIYVYTKLQNTEYRKHFPQTHSPNKPQCD
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.84
Interspecies Antigen Sequence
Mouse (70); Rat (64)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — RNASEL
Entrez GeneID
6041GeneBank Accession#
NM_021133Protein Accession#
NP_066956Gene Name
RNASEL
Gene Alias
DKFZp781D08126, MGC104972, MGC133329, PRCA1, RNS4
Gene Description
ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
Gene Ontology
HyperlinkGene Summary
This gene encodes a component of the interferon-regulated 2-5A system that functions in the antiviral and antiproliferative roles of interferons. Mutations in this gene have been associated with predisposition to prostate cancer and this gene is a candidate for the hereditary prostate cancer 1 (HPC1) allele. [provided by RefSeq
Other Designations
2',5'-oligoisoadenylate synthetase-dependent|OTTHUMP00000033148|interferon-induced 2-5A-dependent RNase|ribonuclease 4|ribonuclease L
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Interactomes
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Diseases
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