RNASEL monoclonal antibody (M01), clone 3B4
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant RNASEL.
Immunogen
RNASEL (NP_066956, 619 a.a. ~ 728 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
QPGPSEHSKSFDKWTTKINECVMKKMNKFYEKRGNFYQNTVGDLLKFIRNLGEHIDEEKHKKMKLKIGDPSLYFQKTFPDLVIYVYTKLQNTEYRKHFPQTHSPNKPQCD
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (70); Rat (64)
Isotype
IgG1 kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged RNASEL is approximately 0.1ng/ml as a capture antibody.ELISA
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Gene Info — RNASEL
Entrez GeneID
6041GeneBank Accession#
NM_021133Protein Accession#
NP_066956Gene Name
RNASEL
Gene Alias
DKFZp781D08126, MGC104972, MGC133329, PRCA1, RNS4
Gene Description
ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
Gene Ontology
HyperlinkGene Summary
This gene encodes a component of the interferon-regulated 2-5A system that functions in the antiviral and antiproliferative roles of interferons. Mutations in this gene have been associated with predisposition to prostate cancer and this gene is a candidate for the hereditary prostate cancer 1 (HPC1) allele. [provided by RefSeq
Other Designations
2',5'-oligoisoadenylate synthetase-dependent|OTTHUMP00000033148|interferon-induced 2-5A-dependent RNase|ribonuclease 4|ribonuclease L
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Interactome
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Disease
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