RAD1 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Western Blot (Transfected lysate)
Western Blot analysis of RAD1 expression in transfected 293T cell line (H00005810-T01) by RAD1 MaxPab polyclonal antibody.
Lane 1: RAD1 transfected lysate(31.02 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to RAD1 on HeLa cell. [antibody concentration 10 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human RAD1 protein.
Immunogen
RAD1 (NP_002844, 1 a.a. ~ 282 a.a) full-length human protein.
Sequence
MPLLTQQIQDEDDQYSLVASLDNVRNLSTILKAIHFREHATCFATKNGIKVTVENAKCVQANAFIQAGIFQEFKVQEESVTFRINLTVLLDCLSIFGSSPMPGTLTALRMCYQGYGYPLMLFLEEGGVVTVCKINTQEPEETLDFDFCSTNVINKIILQSEGLREAFSELDMTSEVLQITMSPDKPYFRLSTFGNAGSSHLDYPKDSDLMEAFHCNQTQVNRYKISLLKPSTKALVLSCKVSIRTDNRGFLSLQYMIRNEDGQICFVEYYCCPDEEVPESES
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of RAD1 expression in transfected 293T cell line (H00005810-T01) by RAD1 MaxPab polyclonal antibody.
Lane 1: RAD1 transfected lysate(31.02 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to RAD1 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — RAD1
Entrez GeneID
5810GeneBank Accession#
NM_002853Protein Accession#
NP_002844Gene Name
RAD1
Gene Alias
HRAD1, REC1
Gene Description
RAD1 homolog (S. pombe)
Omim ID
603153Gene Ontology
HyperlinkGene Summary
This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described. [provided by RefSeq
Other Designations
DNA repair exonuclease REC1|OTTHUMP00000115992|RAD1 homolog|Rad1-like DNA damage checkpoint|cell cycle checkpoint protein Hrad1|checkpoint control protein HRAD1|exonuclease homolog RAD1
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Interactome
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Disease
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