MMP3 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-MMP3 full-length
Host
Human
Theoretical MW (kDa)
54
Interspecies Antigen Sequence
Mouse (77); Rat (75)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-MMP3 antibody (H00004314-B01) by Western Blots.
SDS-PAGE Gel
MMP3 transfected lysate
Western Blot
Lane 1: MMP3 transfected lysate ( 54 KDa).
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — MMP3
Entrez GeneID
4314GeneBank Accession#
NM_002422Protein Accession#
NP_002413Gene Name
MMP3
Gene Alias
CHDS6, MGC126102, MGC126103, MGC126104, MMP-3, SL-1, STMY, STMY1, STR1
Gene Description
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
Omim ID
185250Gene Ontology
HyperlinkGene Summary
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq
Other Designations
matrix metalloproteinase 3|matrix metalloproteinase 3 (stromelysin 1, progelatinase)|progelatinase|proteoglycanase|stromelysin 1|transin-1
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Interactome
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