LNPEP (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human LNPEP partial ORF ( NP_005566, 926 a.a. - 1025 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
FIIRTVGRHFPGHLLAWDFVKENWNKLVQKFPLGSYTIQNIVAGSTYLFSTKTHLSEVQAFFENQSEATFRLRCVQEALEVIQLNIQWMEKNLKSLTWWL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (88)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — LNPEP
Entrez GeneID
4012GeneBank Accession#
NM_005575Protein Accession#
NP_005566Gene Name
LNPEP
Gene Alias
CAP, IRAP, P-LAP, PLAP
Gene Description
leucyl/cystinyl aminopeptidase
Omim ID
151300Gene Ontology
HyperlinkGene Summary
This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
AT (4) receptor|OTTHUMP00000196800|angiotensin IV receptor|insulin-regulated aminopeptidase|insulin-responsive aminopeptidase|otase|oxytocinase|placental leucine aminopeptidase|vasopressinase
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Interactome
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Pathway
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Disease
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