CYP2E1 (Human) IP-WB Antibody Pair
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (78%); Rat (78%)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of CYP2E1 transfected lysate using rabbit polyclonal anti-CYP2E1 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-CYP2E1.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-CYP2E1 (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-CYP2E1 (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — CYP2E1
Entrez GeneID
1571Gene Name
CYP2E1
Gene Alias
CPE1, CYP2E, P450-J, P450C2E
Gene Description
cytochrome P450, family 2, subfamily E, polypeptide 1
Omim ID
124040Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer. [provided by RefSeq
Other Designations
OTTHUMP00000020813|OTTHUMP00000046571|cytochrome P450 2E1|cytochrome P450, subfamily IIE (ethanol-inducible), polypeptide 1|flavoprotein-linked monooxygenase|microsomal monooxygenase|xenobiotic monooxygenase
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Interactome
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Disease
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