CTLA4 monoclonal antibody (M26), clone 1D3
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More Files
- More Functions
Western Blot (Cell lysate)
CTLA4 monoclonal antibody (M26), clone 1D3. Western Blot analysis of CTLA4 expression in HeLa.
Western Blot (Cell lysate)
CTLA4 monoclonal antibody (M26), clone 1D3. Western Blot analysis of CTLA4 expression in Jurkat.
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CTLA4.
Immunogen
CTLA4 (AAH74842.1, 37 a.a. ~ 161 a.a) partial recombinant protein.
Sequence
AMHVAQPAVVLASSRGIASFVCEYASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFLDDSICTGTSSGNQVNLTIQGLRAMDTGLYICKVELMYPPPYYLGIGNGTQIYVIDPEPCPDSD
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (68); Rat (72)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
CTLA4 monoclonal antibody (M26), clone 1D3. Western Blot analysis of CTLA4 expression in HeLa.Western Blot (Cell lysate)
CTLA4 monoclonal antibody (M26), clone 1D3. Western Blot analysis of CTLA4 expression in Jurkat.ELISA
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Gene Info — CTLA4
Entrez GeneID
1493GeneBank Accession#
BC074842Protein Accession#
AAH74842.1Gene Name
CTLA4
Gene Alias
CD152, CELIAC3, CTLA-4, GSE, IDDM12
Gene Description
cytotoxic T-lymphocyte-associated protein 4
Gene Ontology
HyperlinkGene Summary
This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq
Other Designations
OTTHUMP00000163781|cytotoxic T-lymphocyte-associated antigen 4|cytotoxic T-lymphocyte-associated serine esterase-4|ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4
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Interactome
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Pathway
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Disease
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