TPP1 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
TPP1 MaxPab rabbit polyclonal antibody. Western Blot analysis of TPP1 expression in human placenta.
Western Blot (Cell lysate)
TPP1 MaxPab rabbit polyclonal antibody. Western Blot analysis of TPP1 expression in Jurkat.
Western Blot (Transfected lysate)
Western Blot analysis of TPP1 expression in transfected 293T cell line (H00001200-T01) by TPP1 MaxPab polyclonal antibody.
Lane 1: TPP1 transfected lysate(61.20 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human TPP1 protein.
Immunogen
TPP1 (NP_000382.3, 1 a.a. ~ 563 a.a) full-length human protein.
Sequence
MGLQACLLGLFALILSGKCSYSPEPDQRRTLPPGWVSLGRADPEEELSLTFALRQQNVERLSELVQAVSDPSSPQYGKYLTLENVADLVRPSPLTLHTVQKWLLAAGAQKCHSVITQDFLTCWLSIRQAELLLPGAEFHHYVGGPTETHVVRSPHPYQLPQALAPHVDFVGGLHRFPPTSSLRQRPEPQVTGTVGLHLGVTPSVIRKRYNLTSQDVGSGTSNNSQACAQFLEQYFHDSDLAQFMRLFGGNFAHQASVARVVGQQGRGRAGIEASLDVQYLMSAGANISTWVYSSPGRHEGQEPFLQWLMLLSNESALPHVHTVSYGDDEDSLSSAYIQRVNTELMKAAARGLTLLFASGDSGAGCWSVSGRHQFRPTFPASSPYVTTVGGTSFQEPFLITNEIVDYISGGGFSNVFPRPSYQEEAVTKFLSSSPHLPPSSYFNASGRAYPDVAALSDGYWVVSNRVPIPWVSGTSASTPVFGGILSLINEHRILSGRPPLGFLNPRLYQQHGAGLFDVTRGCHESCLDEEVEGQGFCSGPGWDPVTGWGTPNFPALLKTLLNP
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (88)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
TPP1 MaxPab rabbit polyclonal antibody. Western Blot analysis of TPP1 expression in human placenta.Western Blot (Cell lysate)
TPP1 MaxPab rabbit polyclonal antibody. Western Blot analysis of TPP1 expression in Jurkat.Western Blot (Transfected lysate)
Western Blot analysis of TPP1 expression in transfected 293T cell line (H00001200-T01) by TPP1 MaxPab polyclonal antibody.
Lane 1: TPP1 transfected lysate(61.20 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — TPP1
Entrez GeneID
1200GeneBank Accession#
NM_000391Protein Accession#
NP_000382.3Gene Name
TPP1
Gene Alias
CLN2, GIG1, LPIC, MGC21297
Gene Description
tripeptidyl peptidase I
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq
Other Designations
ceroid-lipofuscinosis, neuronal 2, late infantile (Jansky-Bielschowsky disease)|growth-inhibiting protein 1|lysosomal pepstatin insensitive protease|tripeptidyl aminopeptidase|tripeptidyl-peptidase I
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Interactome
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Pathway
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Disease
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