TPP1 (Human) Matched Antibody Pair
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Specifications
Product Description
This antibody pair set comes with a matched antibody pair to detect and quantify the protein level of human TPP1.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (88%); Rat (87%)
Quality Control Testing
Standard curve using TPP1 293T overexpression lysate (non-denatured) as an analyte.
Sandwich ELISA detection sensitivity ranging from approximately 729x to 3x dilution of the TPP1 293T overexpression lysate (non-denatured).
Supplied Product
Antibody pair set content:
1. Capture antibody: mouse monoclonal anti-TPP1 (100 ug)
2. Detection antibody: rabbit purified polyclonal anti-TPP1 (50 ug)
*Reagents are sufficient for at least 3-5 x 96 well plates using recommended protocols.Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
ELISA Pair (Transfected lysate)
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Gene Info — TPP1
Entrez GeneID
1200Gene Name
TPP1
Gene Alias
CLN2, GIG1, LPIC, MGC21297
Gene Description
tripeptidyl peptidase I
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq
Other Designations
ceroid-lipofuscinosis, neuronal 2, late infantile (Jansky-Bielschowsky disease)|growth-inhibiting protein 1|lysosomal pepstatin insensitive protease|tripeptidyl aminopeptidase|tripeptidyl-peptidase I
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Interactomes
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Pathways
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Diseases
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