CDH2 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human CDH2 partial ORF ( NP_001783, 807 a.a. - 906 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
RRMDERPIHAEPQYPVRSAAPHPGDIGDFINEGLKAADNDPTAPPYDSLLVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRFKKLADMYGGGDD
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (98)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CDH2
Entrez GeneID
1000GeneBank Accession#
NM_001792Protein Accession#
NP_001783Gene Name
CDH2
Gene Alias
CD325, CDHN, CDw325, NCAD
Gene Description
cadherin 2, type 1, N-cadherin (neuronal)
Omim ID
114020Gene Ontology
HyperlinkGene Summary
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product. [provided by RefSeq
Other Designations
N-cadherin 1|cadherin 2, N-cadherin (neuronal)|cadherin 2, type 1|calcium-dependent adhesion protein, neuronal|neural cadherin
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Interactome
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Pathway
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Disease
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