CA12 MaxPab rabbit polyclonal antibody (D01)
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human CA12 protein.
Immunogen
CA12 (NP_001209.1, 1 a.a. ~ 354 a.a) full-length human protein.
Sequence
MPRRSLHAAAVLLLVILKEQPSSPAPVNGSKWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSDMHIQGLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTSFSQVQVCTAAGLSLGIILSLALAGILGICIVVVVSIWLFRRKSIKKGDNKGVIYKPATKMETEAHA
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (82); Rat (81)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
CA12 MaxPab rabbit polyclonal antibody. Western Blot analysis of CA12 expression in MCF-7.Western Blot (Transfected lysate)
Western Blot analysis of CA12 expression in transfected 293T cell line (H00000771-T01) by CA12 MaxPab polyclonal antibody.
Lane 1: CA12 transfected lysate(39.50 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of CA12 transfected lysate using anti-CA12 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with CA12 MaxPab mouse polyclonal antibody (B01) (H00000771-B01). -
Gene Info — CA12
Entrez GeneID
771GeneBank Accession#
NM_001218.3Protein Accession#
NP_001209.1Gene Name
CA12
Gene Alias
CAXII, FLJ20151, HsT18816
Gene Description
carbonic anhydrase XII
Omim ID
603263Gene Ontology
HyperlinkGene Summary
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Two transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq
Other Designations
carbonic dehydratase
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Interactome
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Pathway
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