CA11 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-CA11 full-length
Host
Human
Theoretical MW (kDa)
36.2
Interspecies Antigen Sequence
Mouse (97); Rat (97)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-CA11 antibody (H00000770-B02P) by Western Blots.
SDS-PAGE Gel
CA11 transfected lysate.
Western Blot
Lane 1: CA11 transfected lysate ( 36.2 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — CA11
Entrez GeneID
770GeneBank Accession#
NM_001217.3Protein Accession#
NP_001208.2Gene Name
CA11
Gene Alias
CARP2, CARPX1
Gene Description
carbonic anhydrase XI
Omim ID
604644Gene Ontology
HyperlinkGene Summary
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XI is likely a secreted protein, however, radical changes at active site residues completely conserved in CA isozymes with catalytic activity, make it unlikely that it has carbonic anhydrase activity. It shares properties in common with two other acatalytic CA isoforms, CA VIII and CA X. CA XI is most abundantly expressed in brain, and may play a general role in the central nervous system. [provided by RefSeq
Other Designations
carbonic anhydrase-related protein 2|carbonic anhydrase-related protein XI
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