SERPINC1 monoclonal antibody (M02), clone 2B12
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More Files
- More Functions
Western Blot (Tissue lysate)
SERPINC1 monoclonal antibody (M02), clone 2B12. Western Blot analysis of SERPINC1 expression in human kidney.
Western Blot (Transfected lysate)
Western Blot analysis of SERPINC1 expression in transfected 293T cell line by SERPINC1 monoclonal antibody (M02), clone 2B12.
Lane 1: SERPINC1 transfected lysate(29.1 KDa).
Lane 2: Non-transfected lysate.
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SERPINC1 is 3 ng/ml as a capture antibody.
Western Blot detection against Immunogen (54.23 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant SERPINC1.
Immunogen
SERPINC1 (AAH22309.1, 1 a.a. ~ 259 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MYSNVIGTVTSGKRKVYLLSLLLIGFWDCVTCHGSPVDICTAEPRDIPMNPMCIYRSPEKKATEDEGSEQKIPEATNRRVWELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRVANPCVK
Host
Mouse
Reactivity
Human
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (54.23 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
SERPINC1 monoclonal antibody (M02), clone 2B12. Western Blot analysis of SERPINC1 expression in human kidney.Western Blot (Transfected lysate)
Western Blot analysis of SERPINC1 expression in transfected 293T cell line by SERPINC1 monoclonal antibody (M02), clone 2B12.
Lane 1: SERPINC1 transfected lysate(29.1 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SERPINC1 is 3 ng/ml as a capture antibody.ELISA
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Gene Info — SERPINC1
Entrez GeneID
462GeneBank Accession#
BC022309Protein Accession#
AAH22309.1Gene Name
SERPINC1
Gene Alias
AT3, ATIII, MGC22579
Gene Description
serpin peptidase inhibitor, clade C (antithrombin), member 1
Omim ID
107300Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency. [provided by RefSeq
Other Designations
OTTHUMP00000035393|antithrombin (aa 375-432)|antithrombin III|coding sequence signal peptide antithrombin part 1|serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1|signal peptide antithrombin part 1
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Interactome
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Pathway
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Disease
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Publication Reference
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The Rheumatoid Arthritis-Associated Citrullinome.
Tilvawala R, Nguyen SH, Maurais AJ, Nemmara VV, Nagar M, Salinger AJ, Nagpal S, Weerapana E, Thompson PR.
Cell Chemical Biology 2018 Mar; [Epub].
Application：ELISA, Human, Serum, synovial fluid.
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The Rheumatoid Arthritis-Associated Citrullinome.
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