SERPINC1 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Western Blot (Tissue lysate)
SERPINC1 MaxPab polyclonal antibody. Western Blot analysis of SERPINC1 expression in human kidney.
Western Blot (Transfected lysate)
Western Blot analysis of SERPINC1 expression in transfected 293T cell line (H00000462-T01) by SERPINC1 MaxPab polyclonal antibody.
Lane 1: SERPINC1 transfected lysate(28.49 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human SERPINC1 protein.
Immunogen
SERPINC1 (AAH22309.1, 1 a.a. ~ 259 a.a) full-length human protein.
Sequence
MYSNVIGTVTSGKRKVYLLSLLLIGFWDCVTCHGSPVDICTAKPRDIPMNPMCIYRSPEKKATEDEGSEQKIPEATNRRVWELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRVANPCVK
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
SERPINC1 MaxPab polyclonal antibody. Western Blot analysis of SERPINC1 expression in human kidney.Western Blot (Transfected lysate)
Western Blot analysis of SERPINC1 expression in transfected 293T cell line (H00000462-T01) by SERPINC1 MaxPab polyclonal antibody.
Lane 1: SERPINC1 transfected lysate(28.49 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — SERPINC1
Entrez GeneID
462GeneBank Accession#
BC022309.1Protein Accession#
AAH22309.1Gene Name
SERPINC1
Gene Alias
AT3, ATIII, MGC22579
Gene Description
serpin peptidase inhibitor, clade C (antithrombin), member 1
Omim ID
107300Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency. [provided by RefSeq
Other Designations
OTTHUMP00000035393|antithrombin (aa 375-432)|antithrombin III|coding sequence signal peptide antithrombin part 1|serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1|signal peptide antithrombin part 1
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Interactome
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Pathway
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Disease
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