STS polyclonal antibody (A01)
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Specifications
Product Description
Mouse polyclonal antibody raised against a partial recombinant STS.
Immunogen
STS (NP_000342, 248 a.a. ~ 350 a.a) partial recombinant protein with GST tag.
Sequence
YEIIQQPMSYDNLTQRLTVEAAQFIQRNTETPFLLVLSYLHVHTALFSSKDFAGKSQHGVYGDAVEEMDWSVGQILNLLDELRLANDTLIYFTSDQGAHVEEV
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.44 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — STS
Entrez GeneID
412GeneBank Accession#
NM_000351Protein Accession#
NP_000342Gene Name
STS
Gene Alias
ARSC, ARSC1, ASC, ES, SSDD
Gene Description
steroid sulfatase (microsomal), isozyme S
Omim ID
308100Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene catalyzes the conversion of sulfated steroid precursors to estrogens during pregnancy. The encoded protein is found in the endoplasmic reticulum, where it acts as a homodimer. Mutations in this gene are known to cause X-linked ichthyosis (XLI). [provided by RefSeq
Other Designations
OTTHUMP00000022868|arylsulfatase C|estrone sulfatase|steryl-sulfatase|steryl-sulfate sulfohydrolase
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Interactomes
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Pathways
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Diseases
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Publication Reference
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Validation of murine and human placental explant cultures for use in sex steroid and phase II conjugation toxicology studies.
Sato BL, Ward MA, Astern JM, Kendal-Wright CE, Collier AC.
Toxicology in Vitro 2015 Feb; 29(1):103.
Application:WB-Ti, Human, Placental.
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In situ levels of oestrogen producing enzymes and its prognostic significance in postmenopausal breast cancer patients.
Licznerska BE, Wegman PP, Nordenskjold B, Wingren S.
Breast Cancer Research and Treatment 2007 Nov; 112(1):15.
Application:IHC-P, Human, Postmenopausal patients with a breast cancer.
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Validation of murine and human placental explant cultures for use in sex steroid and phase II conjugation toxicology studies.
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