BIRC3 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-BIRC3 full-length
Host
Human
Theoretical MW (kDa)
68.4
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-BIRC3 antibody (H00000330-B01) by Western Blots.
SDS-PAGE Gel
BIRC3 transfected lysate.
Western Blot
Lane 1: BIRC3 transfected lysate ( 68.4 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — BIRC3
Entrez GeneID
330GeneBank Accession#
NM_001165Protein Accession#
NP_001156Gene Name
BIRC3
Gene Alias
AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49
Gene Description
baculoviral IAP repeat-containing 3
Omim ID
601721Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq
Other Designations
TNFR2-TRAF signaling complex protein|apoptosis inhibitor 2|baculoviral IAP repeat-containing protein 3|inhibitor of apoptosis protein 1|mammalian IAP homolog C
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Interactome
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Pathway
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Disease
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Publication Reference
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Cellular inhibitor of apoptosis protein 2 (cIAP2) controls human colonic epithelial restitution, migration and Rac1 activation.
Seidelin JB, Larsen S, Linnemann D, Vainer B, Coskun M, Troelsen JT, Nielsen OH.
American Journal of Physiology. Gastrointestinal and Liver Physiology 2015 Jan; 308(2):G92.
Application:WB-Tr, Human, HEK-293T cells.
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Cellular inhibitor of apoptosis protein 2 (cIAP2) controls human colonic epithelial restitution, migration and Rac1 activation.
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