APEX1 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
APEX1 MaxPab polyclonal antibody. Western Blot analysis of APEX1 expression in human liver.
Western Blot (Transfected lysate)
Western Blot analysis of APEX1 expression in transfected 293T cell line (H00000328-T01) by APEX1 MaxPab polyclonal antibody.
Lane 1: APEX1 transfected lysate(34.98 KDa).
Lane 2: Non-transfected lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of purified MaxPab antibody to APEX1 on formalin-fixed paraffin-embedded human stomach. [antibody concentration 1.5 ug/ml]
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to APEX1 on HeLa cell. [antibody concentration 10 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human APEX1 protein.
Immunogen
APEX1 (NP_001632, 1 a.a. ~ 318 a.a) full-length human protein.
Sequence
MPKRGKKGAVAEDGDELRTEPEAKKSKTAAKKNDKEAAGEGPALYEDPPDHKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQCPLKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
APEX1 MaxPab polyclonal antibody. Western Blot analysis of APEX1 expression in human liver.Western Blot (Transfected lysate)
Western Blot analysis of APEX1 expression in transfected 293T cell line (H00000328-T01) by APEX1 MaxPab polyclonal antibody.
Lane 1: APEX1 transfected lysate(34.98 KDa).
Lane 2: Non-transfected lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of purified MaxPab antibody to APEX1 on formalin-fixed paraffin-embedded human stomach. [antibody concentration 1.5 ug/ml]Immunofluorescence
Immunofluorescence of purified MaxPab antibody to APEX1 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — APEX1
Entrez GeneID
328GeneBank Accession#
NM_001641Protein Accession#
NP_001632Gene Name
APEX1
Gene Alias
APE, APE-1, APE1, APEN, APEX, APX, HAP1, REF-1, REF1
Gene Description
APEX nuclease (multifunctional DNA repair enzyme) 1
Omim ID
107748Gene Ontology
HyperlinkGene Summary
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq
Other Designations
AP endonuclease class I|AP lyase|APEX nuclease|DNA-(apurinic or apyrimidinic site) lyase|OTTHUMP00000163988|apurinic/apyrimidinic (abasic) endonuclease|apurinic/apyrimidinic exonuclease|deoxyribonuclease (apurinic or apyrimidinic)|multifunctional DNA repa
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Interactome
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Pathway
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Disease
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