ALDH3A1 monoclonal antibody (M08), clone 2G4
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More Files
- More Functions
Immunoprecipitation
Immunoprecipitation of ALDH3A1 transfected lysate using anti-ALDH3A1 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with ALDH3A1 MaxPab rabbit polyclonal antibody.
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ALDH3A1 is approximately 1ng/ml as a capture antibody.
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant ALDH3A1.
Immunogen
ALDH3A1 (AAH04370, 1 a.a. ~ 453 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MSKISEAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAYYEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNLTIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQYLDKDLYPVINGGVPETTELLKERFDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEGQKVAYGGTGDAATRYIAPTILTDGDPQSPVMQEEIFGPVLPIVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFETFSHRRSCLVRPLMNDGGLKVRYPPSPAKMTQH
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (80); Rat (81)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Immunoprecipitation
Immunoprecipitation of ALDH3A1 transfected lysate using anti-ALDH3A1 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with ALDH3A1 MaxPab rabbit polyclonal antibody.Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ALDH3A1 is approximately 1ng/ml as a capture antibody.ELISA
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Gene Info — ALDH3A1
Entrez GeneID
218GeneBank Accession#
BC004370Protein Accession#
AAH04370Gene Name
ALDH3A1
Gene Alias
ALDH3, ALDHIII, MGC10406
Gene Description
aldehyde dehydrogenase 3 family, memberA1
Omim ID
100660Gene Ontology
HyperlinkGene Summary
Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq
Other Designations
aldehyde dehydrogenase 3A1|aldehyde dehydrogenase isozyme 3|aldehyde dehydrogenase type III|aldehyde dehydrogenase, dimeric NADP-preferring|stomach aldehyde dehydrogenase
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Interactome
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Pathway
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Disease
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