CNR2 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
CNR2 polyclonal antibody (Cat # PAB6877) (2 ug/mL) staining of Jurkat lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of CNR2.
Immunogen
A synthetic peptide corresponding to human CNR2.
Sequence
C-TETEADGKITPWPD
Host
Goat
Theoretical MW (kDa)
46.2
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:16000)
Western Blot (2-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
CNR2 polyclonal antibody (Cat # PAB6877) (2 ug/mL) staining of Jurkat lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CNR2
Entrez GeneID
1269Protein Accession#
NP_001832.1Gene Name
CNR2
Gene Alias
CB2, CX5
Gene Description
cannabinoid receptor 2 (macrophage)
Omim ID
605051Gene Ontology
HyperlinkGene Summary
The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors. [provided by RefSeq
Other Designations
OTTHUMP00000015772|OTTHUMP00000044841
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Interactome
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Pathway
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Disease
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Publication Reference
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Identification and functional characterization of brainstem cannabinoid CB2 receptors.
Van Sickle MD, Duncan M, Kingsley PJ, Mouihate A, Urbani P, Mackie K, Stella N, Makriyannis A, Piomelli D, Davison JS, Marnett LJ, Di Marzo V, Pittman QJ, Patel KD, Sharkey KA.
Science 2005 Oct; 310(5746):329.
Application：IF, WB-Ti, Rat, Rat brains.
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Identification and functional characterization of brainstem cannabinoid CB2 receptors.
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