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- Home > Products > Polyclonal Ab > Human > Enzyme > Phosphatase > PHLPP1 polyclonal antibody
PHLPP1 polyclonal antibody
- Catalog # : PAB3527
- Visit Frequency :
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- 100 ug
- USD $ 319
- order now, ship in 5 days
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Email : sales@abnova.com
Phone : +1-909-992-0619 (new)
Fax : +1-909-992-3401- Products will be shipped directly to the customer.
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of PHLPP1.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human PHLPP1.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:50-100)
The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- The phosphatase PHLPP controls the cellular levels of protein kinase C.
Gao T, Brognard J, Newton AC.J Biol Chem. 2008 Mar 7;283(10):6300-11. Epub 2007 Dec 27.
- 2.
- PHLPP and a second isoform, PHLPP2, differentially attenuate the amplitude of Akt signaling by regulating distinct Akt isoforms.
Brognard J, Sierecki E, Gao T, Newton AC.Mol Cell. 2007 Mar 23;25(6):917-31.
- 3.
- PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth.
Gao T, Furnari F, Newton AC.Mol Cell. 2005 Apr 1;18(1):13-24.
- Entrez GeneID:
- 23239
- Protein Accession#:
- O60346
- Gene Name:
- PHLPP1
- Gene Alias:
- MGC161555,PHLPP1,PLEKHE1,SCOP,PHLPP
- Gene Description:
- PH domain and leucine rich repeat protein phosphatase 1
- Omim ID:
- 609396
- Gene Ontology:
- Hyperlink
- Other Designations:
- PH domain leucine-rich repeat-containing protein phosphatase 1; PH domain-containing family E member 1; SCN circadian oscillatory protein; pleckstrin homology domain containing, family E (with leucine rich repeats) member 1; suprachiasmatic nucleus circad
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