AADAT polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human kidney tissue with AADAT polyclonal antibody (Cat # PAB27815). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of AADAT.
Immunogen
A synthetic peptide corresponding to 17 amino acid at internal region of human AADAT.
Host
Rabbit
Reactivity
Human
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Form
Liquid
Purification
Immunoaffinity chromatography
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human kidney tissue with AADAT polyclonal antibody (Cat # PAB27815). Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. -
Gene Info — AADAT
Entrez GeneID
51166Protein Accession#
Q8N5Z0Gene Name
AADAT
Gene Alias
KAT2, KATII
Gene Description
aminoadipate aminotransferase
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Two alternative transcripts encoding the same isoform have been identified, however, additional alternative transcripts and isoforms may exist. [provided by RefSeq
Other Designations
L kynurenine/alpha aminoadipate aminotransferase|L-kynurenine/alpha-aminoadipate aminotransferase|alpha-aminoadipate aminotransferase|kynurenine aminotransferase II
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Interactome
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Pathway
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