TAP1 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
TAP1 polycolnal antibody (Cat # PAB27600) (1ug/ml) staining of MCF7 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of TAP1.
Immunogen
A synthetic peptide corresponding to internal region of human TAP1.
Sequence
QKFREKLQEIKT
Host
Goat
Theoretical MW (kDa)
85
Reactivity
Human
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:32000)
Western Blot (1-3ug/ml)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
TAP1 polycolnal antibody (Cat # PAB27600) (1ug/ml) staining of MCF7 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. -
Gene Info — TAP1
Entrez GeneID
6890Protein Accession#
NP_000584.2Gene Name
TAP1
Gene Alias
ABC17, ABCB2, APT1, D6S114E, FLJ26666, FLJ41500, PSF1, RING4, TAP1*0102N, TAP1N
Gene Description
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
Gene Ontology
HyperlinkGene Summary
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. [provided by RefSeq
Other Designations
ABC transporter, MHC 1|ATP-binding cassette transporter|ATP-binding cassette, sub-family B (MDR/TAP), member 2|ATP-binding cassette, sub-family B, member 2|OTTHUMP00000029077|antigen peptide transporter 1|peptide supply factor 1|transporter 1, ATP-binding
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Interactome
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Pathway
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Disease
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