KCNJ11 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of KCNJ11.
Immunogen
A synthetic peptide corresponding to residues surrounding T224 of human KCNJ11.
Host
Rabbit
Reactivity
Human, Mouse
Specificity
This antibody is specific to KCNJ11.
Form
Liquid
Purification
Affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:100)
Immunofluorescence (1:500-1:1000)
ELISA (1:10000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from HeLa cells (Lane 1) and NIH-3T3 cells (Lane 2 and 3), treated with heat shock, using KCNJ11 polyclonal antibody (Cat # PAB18408).
Peptide "+" means "peptide blocking".Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human brain tissue using KCNJ11 polyclonal antibody (Cat # PAB18408).
Peptide "+" means "peptide blocking".Immunofluorescence
Immunofluorescence analysis of HeLa cells, using KCNJ11 polyclonal antibody (Cat # PAB18408).
Peptide "+" means "peptide blocking".Enzyme-linked Immunoabsorbent Assay
-
Gene Info — KCNJ11
Entrez GeneID
3767Protein Accession#
Q14654Gene Name
KCNJ11
Gene Alias
BIR, HHF2, IKATP, KIR6.2, MGC133230, PHHI, TNDM3
Gene Description
potassium inwardly-rectifying channel, subfamily J, member 11
Gene Ontology
HyperlinkGene Summary
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). [provided by RefSeq
Other Designations
ATP-sensitive inward rectifier potassium channel 11|beta-cell inward rectifier subunit|inwardly rectifying potassium channel KIR6.2|potassium inwardly-rectifying channel J11
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com