AHR polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of extracts from 293 cells, using AHR polyclonal antibody (Cat # PAB18068).
Peptide "+" means "with peptide blocking".
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded human thyroid gland tissue using AHR polyclonal antibody (Cat # PAB18068).
Peptide "+" means "with peptide blocking".
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of AHR.
Immunogen
A synthetic peptide corresponding to residues surrounding S36 of human AHR.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
This antibody is specific to AHR.
Form
Liquid
Recommend Usage
Western Blot (1:500~1:1000)
Immunohistochemistry (1:50~1:100)
Immunofluorescence (1:100~1:500)
ELISA (1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from 293 cells, using AHR polyclonal antibody (Cat # PAB18068).
Peptide "+" means "with peptide blocking".Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded human thyroid gland tissue using AHR polyclonal antibody (Cat # PAB18068).
Peptide "+" means "with peptide blocking".Immunohistochemistry
Immunofluorescence
Enzyme-linked Immunoabsorbent Assay
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Gene Info — AHR
Entrez GeneID
196Protein Accession#
P35869Gene Name
AHR
Gene Alias
bHLHe76
Gene Description
aryl hydrocarbon receptor
Omim ID
600253Gene Ontology
HyperlinkGene Summary
This gene encodes a ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Its ligands included a variety of aromatic hydrocarbons. [provided by RefSeq
Other Designations
AH-receptor|aromatic hydrocarbon receptor
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Interactome
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Disease
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Publication Reference
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The Prognostic Impact of the Aryl Hydrocarbon Receptor (AhR) in Primary Breast Cancer Depends on the Lymph Node Status.
Jeschke U, Zhang X, Kuhn C, Jalaguier S, Colinge J, Pfender K, Mayr D, Ditsch N, Harbeck N, Mahner S, Sixou S, Cavaillès V.
International Journal of Molecular Sciences 2019 Feb; 20(5):E1016.
Application：IHC-P, Human, Human breast cancer.
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The DNA sequence of human chromosome 7.
Hillier LW, Fulton RS, Fulton LA, Graves TA, Pepin KH, Wagner-McPherson C, Layman D, Maas J, Jaeger S, Walker R, Wylie K, Sekhon M, Becker MC, O'Laughlin MD, Schaller ME, Fewell GA, Delehaunty KD, Miner TL, Nash WE, Cordes M, Du H, Sun H, Edwards J, Bradshaw-Cordum H, Ali J, Andrews S, Isak A, Vanbrunt A, Nguyen C, Du F, Lamar B, Courtney L, Kalicki J, Ozersky P, Bielicki L, Scott K, Holmes A, Harkins R, Harris A, Strong CM, Hou S, Tomlinson C, Dauphin-Kohlberg S, Kozlowicz-Reilly A, Leonard S,.
Nature 2003 Jul; 424(6945):157.
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Cloning and expression of a human Ah receptor cDNA.
Dolwick KM, Schmidt JV, Carver LA, Swanson HI, Bradfield CA.
Molecular Pharmacology 1993 Nov; 44(5):911.
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Human Ah receptor cDNA: analysis for highly conserved sequences.
Itoh S, Kamataki T.
Nucleic Acids Research 1993 Jul; 21(15):3578.
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The Prognostic Impact of the Aryl Hydrocarbon Receptor (AhR) in Primary Breast Cancer Depends on the Lymph Node Status.
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