CELF1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CELF1.
Immunogen
A synthetic peptide corresponding to internal of human CELF1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
This antibody detects endogenous levels of total CELF1 protein.
Form
Liquid
Recommend Usage
Western Blot (1:500-1:1000)
ELISA (1:40000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of extracts from HeLa cells (Lane 1 and lane 3) and HepG2 cells (Lane 2), using CELF1 polyclonal antibody (Cat # PAB17427).
Peptide "+" means "with peptide blocking".Enzyme-linked Immunoabsorbent Assay
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Gene Info — CUGBP1
Entrez GeneID
10658Protein Accession#
Q92879Gene Name
CUGBP1
Gene Alias
BRUNOL2, CUG-BP, CUGBP, NAB50, hNab50
Gene Description
CUG triplet repeat, RNA binding protein 1
Omim ID
601074Gene Ontology
HyperlinkGene Summary
Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
CUG RNA-binding protein|CUG triplet repeat, RNA-binding protein 1|bruno-like 2|nuclear polyadenylated RNA-binding protein, 50-kD
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