IL10 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against IL10.
Immunogen
Synthetic protein corresponding to IL10.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Lyophilized
Purification
Protein G chromatography
Isotype
IgG
Recommend Usage
ELISA (1-2 ug/mL)
Western Blot (2-10 ug/mL)
Immunohistochemistry (2-10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from TBS, pH 7.4.
Storage Instruction
Store at -20°C on dry atmosphere.
After reconstitution with PBS/TBS pH 7.4 or other diluents (such as distilled water), store at 2-8°C for one month, or at -20°C for six months without detectable loss of activity.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry
Enzyme-linked Immunoabsorbent Assay
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Gene Info — IL10
Entrez GeneID
3586Protein Accession#
P22301Gene Name
IL10
Gene Alias
CSIF, IL-10, IL10A, MGC126450, MGC126451, TGIF
Gene Description
interleukin 10
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. [provided by RefSeq
Other Designations
cytokine synthesis inhibitory factor
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Interactome
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Pathway
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Disease
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Publication Reference
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Shexiang Baoxin Pill Corrects Metabolic Disorders in a Rat Model of Metabolic Syndrome by Targeting Mitochondria.
Wei D, Zheng N, Zheng L, Wang L, Song L, Sun L.
Frontiers in Pharmacology 2018 Mar; 9:137.
Application:WB-Ti, Rat, Rat adipose tissues.
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Shexiang Baoxin Pill Corrects Metabolic Disorders in a Rat Model of Metabolic Syndrome by Targeting Mitochondria.
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