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DRD2/DRD3 polyclonal antibody   

  • Catalog # : PAB14907
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  • 1 mL
  • USD $ 515
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of DRD2/DRD3.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus human DRD2/DRD3.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Recommend Usage:
  • ELISA (1:400)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In serum
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • ELISA
  • Application Image
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1813
  • Gene Name:
  • DRD2
  • Gene Alias:
  • D2DR,D2R
  • Gene Description:
  • dopamine receptor D2
  • Gene Summary:
  • This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq
  • Other Designations:
  • dopamine receptor D2 isoform,seven transmembrane helix receptor
  • Gene Information
  • Entrez GeneID:
  • 1814
  • Gene Name:
  • DRD3
  • Gene Alias:
  • D3DR,ETM1,FET1,MGC149204,MGC149205
  • Gene Description:
  • dopamine receptor D3
  • Gene Summary:
  • This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD). [provided by RefSeq
  • Other Designations:
  • essential tremor 1
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