DRD2/DRD3 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of DRD2/DRD3.
Immunogen
A synthetic peptide corresponding to C-terminus human DRD2/DRD3.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Recommend Usage
ELISA (1:400)
The optimal working dilution should be determined by the end user.Storage Buffer
In serum
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — DRD2
Entrez GeneID
1813Gene Name
DRD2
Gene Alias
D2DR, D2R
Gene Description
dopamine receptor D2
Gene Ontology
HyperlinkGene Summary
This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq
Other Designations
dopamine receptor D2 isoform|seven transmembrane helix receptor
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Gene Info — DRD3
Entrez GeneID
1814Gene Name
DRD3
Gene Alias
D3DR, ETM1, FET1, MGC149204, MGC149205
Gene Description
dopamine receptor D3
Gene Ontology
HyperlinkGene Summary
This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD). [provided by RefSeq
Other Designations
essential tremor 1
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Interactome
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Pathway
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Disease
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