Rabbit polyclonal antibody raised against synthetic peptide of PDGFRB.
Immunogen:
A synthetic peptide corresponding to C-terminus of human PDGFRB.
Host:
Rabbit
Theoretical MW (kDa):
190
Reactivity:
Human
Form:
Liquid
Purification:
Immunoaffinity purification
Concentration:
Lot specific
Quality Control Testing:
Antibody Reactive Against Synthetic Peptide.
Recommend Usage:
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:50) The optimal working dilution should be determined by the end user.
Storage Buffer:
In 10 mM PBS, pH 7.4 (1% BSA, 0.1% sodium azide)
Storage Instruction:
Store at 4°C.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq