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Last updated: 2014/9/22
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CACNA1C polyclonal antibody

  • Catalog # : PAB11506
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of CACNA1C.
  • Immunogen:
  • A synthetic peptide corresponding to human CACNA1C.
  • Sequence:
  • C-RARGRPSEEELQD
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 240
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • ELISA (1:16000)
    Western Blot (0.5-1.5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • CACNA1C polyclonal antibody (Cat # PAB11506) (0.5 ug/mL) staining of human heart lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 775
  • Gene Name:
  • CACNA1C
  • Gene Alias:
  • CACH2,CACN2,CACNL1A1,CCHL1A1,CaV1.2,MGC120730,TS
  • Gene Description:
  • calcium channel, voltage-dependent, L type, alpha 1C subunit
  • Gene Summary:
  • This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. [provided by RefSeq
  • Other Designations:
  • DHPR, alpha-1 subunit,calcium channel, L type, alpha 1 polypeptide, isoform 1, cardic muscle,calcium channel, cardic dihydropyridine-sensitive, alpha-1 subunit,voltage-gated L-type calcium channel Cav1.2 alpha 1 subunit, splice variant 10*,voltage-gated c
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