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Last updated: 2014/10/20
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ARTN polyclonal antibody

  • Catalog # : PAB0959
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of ARTN.
  • Immunogen:
  • A synthetic peptide corresponding to human ARTN.
  • Sequence:
  • GPGSRARAAGARGC
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of human ARTN in human dorsal root ganglia/CNS preparation with ARTN polyclonal antibody (Cat # PAB0959) at a 1 : 500 dilution.
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 9048
  • Gene Name:
  • ARTN
  • Gene Alias:
  • ENOVIN,EVN,NBN
  • Gene Description:
  • artemin
  • Gene Summary:
  • The protein encoded by this gene is a member of the glial cell line-derived neurotophic factor (GDNF) family of ligands which are a group of ligands within the TGF-beta superfamily of signaling molecules. GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenerative disease. Artemin has been shown in culture to support the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. Its role in the PNS and CNS is further substantiated by its expression pattern in the proximity of these neurons. This protein is a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000009173,OTTHUMP00000009174,neublastin,neurotrophic factor,neurotrophic factor artemin
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